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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
25.45
Human Site:
T461
Identified Species:
43.08
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
T461
L
S
P
K
Q
S
A
T
M
P
K
K
G
I
L
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
T461
L
S
P
K
Q
S
A
T
M
P
K
K
G
I
L
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
T467
L
S
P
K
Q
S
A
T
M
P
K
K
G
I
L
Dog
Lupus familis
XP_538417
666
74288
T466
L
S
P
K
Q
S
A
T
M
P
K
K
G
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
T462
L
S
L
K
Q
S
A
T
M
P
K
K
G
I
L
Rat
Rattus norvegicus
Q66HE5
630
69934
P440
L
R
P
V
S
N
T
P
G
Q
P
V
P
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
T461
H
G
P
K
Q
A
A
T
M
P
K
K
G
I
L
Chicken
Gallus gallus
Q9IA88
798
88848
L453
E
V
R
Q
E
K
E
L
E
D
E
I
K
A
Y
Frog
Xenopus laevis
NP_001088596
570
64876
G380
K
T
P
Q
R
E
S
G
Y
Y
S
S
P
E
H
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
T783
S
A
R
T
L
A
Q
T
L
P
Q
Q
Q
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
P1084
I
P
E
Q
G
A
P
P
Q
P
A
M
R
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S627
I
S
L
L
Q
P
P
S
Y
K
P
S
S
N
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
Q321
E
S
L
R
N
R
T
Q
N
D
A
T
V
T
Y
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
R440
T
A
K
Q
H
A
R
R
M
A
S
A
I
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
80
0
6.6
13.3
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
86.6
20
33.3
53.3
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
29
43
0
0
8
15
8
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% D
% Glu:
15
0
8
0
8
8
8
0
8
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
8
0
0
8
8
0
0
0
43
0
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
0
8
8
43
8
% I
% Lys:
8
0
8
43
0
8
0
0
0
8
43
43
8
0
0
% K
% Leu:
43
0
22
8
8
0
0
8
8
0
0
0
0
0
43
% L
% Met:
0
0
0
0
0
0
0
0
50
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
8
50
0
0
8
15
15
0
58
15
0
15
0
0
% P
% Gln:
0
0
0
29
50
0
8
8
8
8
8
8
8
0
8
% Q
% Arg:
0
8
15
8
8
8
8
8
0
0
0
0
8
0
0
% R
% Ser:
8
50
0
0
8
36
8
8
0
0
15
15
8
0
8
% S
% Thr:
8
8
0
8
0
0
15
50
0
0
0
8
0
15
15
% T
% Val:
0
8
0
8
0
0
0
0
0
0
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _